A Partnership of
Life Science Organizations

Please Log In
E-mail Address


Remember Me

Forget your password?
Reset it here.

Don't have an account?
Register here!

You must log in in order to submit a teaching resource, save or e-mail your searches and resources, review a teaching resource, or participate in community discussions.

Membrane Potential Demo Sheet

View Resource
Excel Spreadsheet (2007)
Average Rating
5.0 out of 5 stars from 1 rating.
Rate It! To rate items you must be logged in to LifeSciTRC.. Log-in/Register now to the left.
Comment On It! To add comments, you must log in or register.
Share It!
Save It! To save the resource to a folder, please log in or register.
Description I provide this excel sheet for students with my assignments and course materials on membrane potential. I believe these exercises help them appreciate the changes in membrane potential due to changes in permeability of the membrane. However, this is not intended to substitute for manual quantitative and calculation skills that students need to master. In some cases, you as the instructor must explain why intervening events prevent a particular value from ever being realized. Examples: -Na channel inactivation prevents the membrane potential from ever reaching the Nernst potential for Na of +60 mV. -K channel inactivation prevents the membrane potential from ever reaching the Nernst potential for K of -90 mV -Also, emphasize the last two scenarios. GABA transmission doesn't greatly alter Vm at rest (because Vm is at the equilibrium potential for Cl. However, when the normal stimulus (glutamate) to reach threshold is input along with GABAergic stimulation, action potential firing is effectively blocked by failing to reach threshold. You can also ask students to come up with (write about) another scenario and what the membrane potential might be under those conditions. In that case, I would give them less scenarios ahead of time than are available in the document.
Type of Resource Assignment/Activity (Non-Laboratory/Non-Hands on Activity)
Format Excel Spreadsheet (2007) - XLSX
Technical Note Microsoft Excel
Dave Knight, Christopher Newport University
Development Date August 12, 2014
Grade/Age Levels Undergraduate upper division (Grades 15-16)
Learning Time 2-3 hours
Language English
Type of Review Reviewed By LifeSciTRC Board
Review Date February 9, 2015
Funding Source None
Suggested Use