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The Nuclear Envelope and Human Disease

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Description Mutations in nuclear lamins A and C, intermediate filament proteins of the nuclear envelope, cause diseases affecting various tissues and the aging process. We review what is known about nuclear lamin function and the different diseases caused by mutations in lamins A and C and associated inner nuclear membrane proteins.
Type of Resource Journal Article/Issue
Format Web Page - HTM
Antoine Muchir, Columbia University
Howard Worman , College of Physicians and Surgeons, Columbia University
Development Date October 1, 2004
Grade/Age Levels Undergraduate lower division (Grades 13-14)
Undergraduate upper division (Grades 15-16)
Professional (degree program)
Continuing Education
General Public
Informal Education
Learning Time <=1 hour
Language English
Type of Review Reviewed By Journal Board
Review Date Reviewed at time of publication
Suggested Use